HE Bishop Serovpé Isakhanyan was born with the baptismal name of Razmik on August 20, 1963 in the village of Hazarjrib in the Iranian province of Peria (pers. Fereydan). In November 1968 he emigrated to Armenia with his parents and other family members. First, the family settled in the village of Khanjyan in the Hoktemberyan region (now Armavir Province), then from 1974 in the city of Etchmiadzin.
He received his schooling in the years 1970 – 1974 in the village school in Khanjyan (Armavir) and afterwards from 1974 – 1980 in Secondary School No. 1 in Etchmiadzin. After successfully graduating from school, in September 1980 he started at the Gevorkian Theological Academy of the Holy Mother See Etchmiadzin enrolled. In November 1981 he was drafted into the Soviet Army for military service. After two years of military service, he continued his studies at the Theological Academy. On February 14, 1986, for the feast of Tyarnendaraj (Presentation of the Lord), he was ordained a deacon by Archbishop Husik Santourian. In 1986 he graduated from the Theological Academy and defended his thesis on "The Ethical Views of Barsegh of Mashkevor", which was awarded with "Excellent".
On June 7, 1987, at feast of Pentecost, Deacon Razmik was ordained a celibate priest by Archbishop Nerses Bosabalian and given the spiritual name Serovpé. In November 1989 he successfully defended his ecclesiastical doctoral thesis "The Ten Commandments and Christ". On November 12 of the same year, he received the Vardapete dignity from Bishop Ashoghik Aristakesyan in the Tatev Monastery.
Between 1987 and 1995 he did church service in Armenia, Moldova and Uzbekistan. In 1995 he began his ministry in the Diocese of the Armenian Church in Germany. Between 2010 and 2018 he was, with a short break, Episcopal Vicar of the Diocese.
After the retirement of Archbishop Karekin Bekdjian, Serovpé Vardapet was elected lieutenant (locum tenens) of the diocesan bishop by the diocesan advisory board. On April 18, 2018, the diocesan assembly of delegates in a secret ballot elected Serovpé Vardapet Isakhanyan as primate of the diocese of the Armenian Apostolic Church in Germany. The election was confirmed by His Holiness Catholicos Karekin II on April 19 of the same year.
On May 12, 2019, on Red Sunday, HE Bishop Serovpé Isakhanyan was consecrated as a bishop in Surb Etchmiadzin by His Holiness Catholicos Karekin II. On May 24, 2019, he was inducted into his office as primate with a festive service.